Distrust and Anxiety

I work in a multinational company. My issue is that though I am well placed, having almost all that a normal person could aspire for, I am not happy, I always have a sense of a feeling that all this is very transient and as a result I’m  in perpetual anxiety not knowing about what.
I also tend to disbelief people (I don’t take  anyone at  their face value) and  I’m always trying to  find meaning in between the  lines. I’ve tried to consciously stop many times, but have not been successful. Help!